, 2009 and Kovacik and Repcak, 2008). Coumarin was detected and quantified in guava, this website passion

fruit, surinam cherry by-products and mango pulp with values ranging from 57.39 to 102.49 μg/g d.b. ( Table 5), results not reported so far in the literature. Coumarin was not detected in the other fruits and by-products samples. The fruits and by-products analyzed in this study were compared to coumarin levels in Lamiaceace family plants and cinnamon bark, which are known to have high concentrations of coumarin and are widely used in traditional medicine and horticulture (such as lavender, salvia, rosemary, oregano, and basil). Levels of coumarin ranged from 14.3 to 276.9 μg/mg dried weight for Lamiaceace family plants, with the genera Lavandula and Salvia showing the highest content ( Lee et al., 2011) and as high as 29.4 mg/g d.b. for ethanolic extract of cinnamon bark ( Ho, Chang, & Chang, 2013). One can see that the content of coumarin in the by-products and pulp observed even if present in lower quantities than cinnamon bark is still considerably higher than other commercially available sources such as Lamiaceace family plants. Consequently,

these fruit by-products and pulp analyzed in this study can be regarded as a rich natural source Epigenetic Reader Domain inhibitor of coumarin. Overall the fruit by-products showed higher (P < 0.05) levels of β-carotene and lycopene, as well as anthocyanins and yellow flavonoids when compared to the fruit pulps studied. Regarding the considerable amounts of anthocyanins, yellow flavonoids and phenolic compounds, our results indicate promising perspectives for the exploitation of these non-traditional tropical fruit species and their by-products with considerable levels of nutrients. The considerable amount of resveratrol and coumarin for some of the fruits and by-products included in this study are likely to draw attention to these species and most importantly to their by-products as potential commodities. Guava and surinam cherry by-products presented

resveratrol in their constitutions and can be considered a rich source of this compound. Similarly, for coumarin, passion fruit, guava and surinam cherry by-products and mango pulp can be considered rich natural sources of coumarin. The data obtained in this study add valuable information ADP ribosylation factor to current knowledge of the nutritional properties of tropical fruits and their by-products, especially if one considers the broad spectrum of properties of the compounds identified. This study showed that agro-industrial by-products are good sources of bioactive compounds and the exploitation of these abundant and low-cost renewable resources could be anticipated for the pharmaceutical and food industries with opportunities of developing new nutraceutical and/or pharmaceutical products, reduction of industrial waste and cost, and ultimately providing a positive economic and environmental impact.