01 and <=.05, respectively), as were long- and short-axis diameters, number, and SUV(max) of distant lymph nodes for reader 1 (P <=.001). With CE CT, size (reader 1) and number (readers 1 and 3) of peritoneal deposits were significantly associated with poor survival (P <=.01),
as were long- and short-axis diameters and number of distant lymph nodes for reader 1 (P <=.01). Interobserver agreement ranged from fair (patient, kappa = 0.30) to moderate (region, kappa = 0.55) for CE CT and fair (patient, kappa = 0.24) to substantial (region, kappa = 0.63) for PET/CT.
Conclusion: Preliminary data suggest that CE CT and PET/CT may have similar accuracy in detection of recurrent ovarian
cancer. Tumor size, number, and SUV(max) may have potential as prognostic biomarkers for patients with recurrent ovarian cancer. (C) RSNA, 2010″
“The local dynamics of ferroelectric domain selleck inhibitor polarization are uniquely investigated with sub-20-nm resolved maps of switching Stem Cell Compound Library purchase times, growth velocities, and growth directions. This is achieved by analyzing movies of hundreds of consecutive high speed piezo force microscopy images, which record domain switching dynamics through repeatedly alternating between high speed domain imaging and the application of 20-nanosecond voltage pulses. Recurrent switching patterns are revealed, and domain wall velocities for nascent domains are uniquely reported to be up to four times faster than for mature domains with radii greater than approximately 100 nm. Switching times, speeds, and directions are also shown to correlate with local mechanical compliance, with domains preferentially nucleating and growing in compliant sample regions while clearly shunting around locations with higher stiffness. This deterministic switching behavior strongly supports a defect-mediated energy landscape which controls polarization reversal, and that can
therefore be predicted, modeled, and even manipulated through composition, HSP990 concentration processing, and geometry. Such results have important implications for the practical performance of ferroelectric devices by enabling guided optimization of switching times and feature densities, while the methods employed provide a new means to investigate and correlate dynamic functionality with mechanical properties at the nanoscale. (C) 2011 American Institute of Physics. [doi:10.1063/1.3581205]“
“Cerebral palsy is the most common neurodevelopmental motor disability in children. The condition requires medical, educational, social, and rehabilitative resources throughout the life span. Several countries have developed population-based registries that serve the purpose of prospective longitudinal collection of etiologic, demographic, and functional severity. The United States has not created a comprehensive program to develop such a registry.