4 32 8 16 32 128 16 128 128 128 32 64 trovafloxacin levofloxacin ciprofloxacin 32,128,128,128 Salmonella spp. 20 492 0.008 0.5 0.008 0.5 0.03 0.06 0.03 0.06 0.06 0.06 ABT trovafloxacin 1 0.015 0.008 0.015 0.03 0.5 levofloxacin ciprofloxacin Shigella spp. ABT 9492 0.002 0.008 NVP-TAE684 TAE684 0.002 0.015 0.004 0.015 0.002 0.015 Ciprofloxacin Levofloxacin Trovafloxacin C. freundii 20 ABT 492 0.03 2 0.25 2 trovafloxacin 0.015 0.5 0.06 0.5 0.25 0.015 0.12 0.25 Levofloxacin 0.12 0.03 0.008 0.12 ciprofloxacin Klebsiella spp.c 20 ABT 492 0.002 0.25 0.06 0.12 0.03 0.06 1 0.015 0.004 Trovafloxacin 0.03 0.06 1 0.004 levofloxacin ciprofloxacin 0, 25 0.015 0.03 K. pneumoniae ABT 492 2 10 8 4 8 4 trovafloxacin 128 128 128 32 64 August 64 levofloxacin ciprofloxacin 64,128,128,128 pp. 19 492 0.008 0.
25 0.015 mirabilis ABT trovafloxacin 0.12 0.12 1 0.5 1 0.015 0.25 0.06 0.12 0.12 0.03 0.12 0.015 levofloxacin ciprofloxacin Enterobacter spp. ABT 20 492 0.004 0.06 0.015 0.03 0.008 0.25 0.03 0.06 Roscovitine 0.06 0.004 Ciprofloxacin Levofloxacin Trovafloxacin 0.03 0.06 0.004 0.03 0.008 0.015 Providencia spp. ABT 20 492 0.015 0.25 0.06 0.25 0.12 1 0.25 0.5 0.12 Levofloxacin Trovafloxacin 1 0.25 0.25 0.015 0.5 0.06 0.25 S. marcescens, ciprofloxacin 10 ABT 492 0.5 2 0.5 2 0.06 0.25 Trovafloxacin 0.12 0.25 0.12 0.06 0.015 0.12 0.015 0.06 0.015 0.03 levofloxacin ciprofloxacin P. aeruginosa ABT 20 492 0 , 03 0.5 0.06 0.25 0.06 2 0.06 2 0.25 0.5 0.25 0.5 0.03 1 Levofloxacin Trovafloxacin 0.06 0.25 P ciprofloxacin. ABT aeruginosa 20 492 8128 32 128 64 128 32,128,128,128 64 128 16 128 64 128 Ciprofloxacin Levofloxacin Trovafloxacin B.
cepacia 3 ABT trovafloxacin levofloxacin 492 8 8 8 8 8 8 8 S. maltophilia ciprofloxacin ABT 492 7 0.008 0.03 0 trovafloxacin February 1 , 5 2 1 0.5 0.25 0.25 4 levofloxacin ciprofloxacin 2 on the n Next page More Continued VOL. 47, 2003 In vitro activity of t of ABT 492 3263 TABLE 1 Number of isolates MIC sort of sequel to antibiotics from 50% to 90% of H. influenzae, ABT 0.002 0.008 25 492 0.002 0.004 0.002 0.015 0.004 0.015 trovafloxacin levofloxacin 0.002 0.015 0.008 0.008 0.002 0.008 0.004 0008 ciprofloxacin H. influenzae ABT 6492 0.004 0.004 0.12 0.06 4 0.5 Levofloxacin Trovafloxacin 0.06 1 0.03 16 1 16 17 M. catarrhalis, ABT ciprofloxacin 492 0.002 0.004 0.002 0.002 0.004 0.008 0.008 0.008 0.008 0.03 0.015 0 trovafloxacin levofloxacin, ciprofloxacin 03 0.
008 0.015 0.015 0.015 L. pneumophila ABT 14 492 0.12 0.12 0.12 0.25 0.25 0.25 0.5 0.5 0.5 Levofloxacin Trovafloxacin Ciprofloxacin 0.5 1 1 1 Legionella spp. ABT 492 5 0.12 0.12 0.25 0.25 0.5 0.5 0.5 1 1 Ciprofloxacin Levofloxacin Trovafloxacin N. gonorrhoeae ABT 492 10 0.004 0.004 0.004 0.004 0.004 0.03 0.03 Levofloxacin Trovafloxacin 0.004 0.06 0.015 0.06 0.004 0.06 0.004 0.008 ciprofloxacin H. pylori ABT 492 45 0.015 0.12 0.03 0.12 0 trovafloxacin 12 0.03 0.5 0.25 0.12 0.5 0.06 0.5 1 1 0.25 0.5 M levofloxacin ciprofloxacin. avium ABT 492 10 2 16 8 16 32 64 32 32 16 64 8128 32 64 Ciprofloxacin Levofloxacin Trovafloxacin August 32 18 M. pneumoniae, ABT 492 0.25 0.5 0.5 0.5 0.12 0.25 0.12 0 , 25 trovafloxacin levofloxacin first February 1 February ciprofloxacin 1 2 2 2 2 C. trachomatis ABT 492 0.03 0.06 0.06 0.12 0.5 0.5 Levofloxacin Trovafloxacin ciprofloxacin B. fragilis ABT 16 492 0.03 0.12 0.06 0 , 12 0.12 0.5 0.25 0.5 1 2 2 2 trovafloxacin levofloxacin ciprofloxacin 16th February 8 April 12 C. ABT difficult trovafloxacin 492 0.015 0.015 0.015 1 1 1 2 4 2 4 16 levofloxacin 16 16 Ciprofloxacin C. perfringens ABT 492 12 0.015 0.015 0.015 0.06 trovafloxacin