Curr Opin Microbiol 2003, 6:338–343.PubMedCrossRef 17. Sanglard D, Hube B, Monod M, Odds FC, Gow NA: A triple
deletion of the secreted aspartyl proteinase genes SAP4 , SAP5 , and SAP6 of Candida albicans causes attenuated virulence. Infect Immun 1997, 65:3539–3546.PubMed 18. Sheppard DC, Yeaman MR, Welch WH, Phan WH, Fu QT, Ibrahim Y, Filler AS, Zhang SG, Waring M, Edwards AJ, Edwards JE: Functional and structural diversity in the Als protein family of Candida albicans . J Biol Chem 2004, 279:30480–30489.PubMedCrossRef 19. Ferreira C, Lucas C: The yeast O -MM-102 acyltransferase Gup1p interferes in Adavosertib molecular weight lipid metabolism with direct consequences on the sphingolipid-sterol-ordered domains integrity/assembly. Biochim Biophys Acta 2008, 1778:2648–2653.PubMedCrossRef 20. Edidin M: The state of lipid-rafts: from model membranes to cells. Annu Rev Biophys Biomol Struct 2003, 32:257–283.PubMedCrossRef 21. Jacobson K, Mouritsen OG, Anderson RG:
Lipid rafts: at a crossroad between cell biology and physics. Nat Cell Biol 2007, 9:7–14.PubMedCrossRef 22. Bosson R, Jaquenoud M, Conzelmann A: GUP1 of Saccharomyces cerevisiae encodes an O -acyltransferase involved in remodelling of the GPI anchor. Mol Biol Cell 2006, 17:2636–2645.PubMedCrossRef 23. Pasrija R, Krishnamurthy S, Prasad T, Ernst J, Prasad R: Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans . J Antimicrob Chemoth 2005, 55:905–913.CrossRef 24. Pasrija R, Prasad T, Prasad R: Membrane INCB024360 in vivo raft lipid constituents affect drug susceptibilities Non-specific serine/threonine protein kinase of Candida albicans . Biochem Soc Trans 2005, 33:1219–1223.PubMedCrossRef 25. Sanglard D, Ischer F, Parkinson T, Falconer D, Bille J: Candida albicans mutations in the ergosterol biosynthetic pathway and resistance
to several antifungal agents. Antimicrob Agents Chemother 2003, 47:2404–2412.PubMedCrossRef 26. Georgopapadakou NH, Walsh TJ: Antifungal agents: chemotherapeutic targets and immunologic strategies. Antimicrob Agents Chemother 1996, 40:279–291.PubMed 27. Song Z, Nes WD: Sterol biosynthesis inhibitors: potential for transition state analogs and mechanism-based inactivators targeted at sterol methyltransferase. Lipids 2007, 42:15–33.PubMedCrossRef 28. Warringer J, Blomberg A: Involvement of yeast YOL151W/ GRE2 in ergosterol metabolism. Yeast 2006, 23:389–398.PubMedCrossRef 29. Holst B, Lunde C, Lages F, Oliveira R, Lucas C, Kielland-Brandt MC: GUP1 and its close homologue GUP2 , encoding multimembrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae . Mol Microbiol 2000, 37:108–124.PubMedCrossRef 30. Ni L, Snyder M: A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae . Mol Biol Cell 2001, 12:2147–2170.PubMed 31. Bonangelino CJ, Chavez EM, Bonifacio JS: Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae .