Gao Q, Thorson JS: The biosynthetic genes encoding

Gao Q, Thorson JS: The biosynthetic genes encoding check details for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. FEMS Microbiol Lett 2008, 282:105–114.CrossRefPubMed

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Biotechnol Lett 2007, 29:57–64.CrossRefPubMed 38. Uguru GC, Stephens KE, Stead JA, Towle JE, Baumberg S, McDowall KJ: Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor. Mol Microbiol 2005, 58:131–150.CrossRefPubMed 39. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29:e45.CrossRefPubMed Authors’ contributions LW carried out the main experimentation and drafted the manuscript. YH and YZ constructed some of the plasmids, SW and ZC participated in fermentation of S. globisporus, YB participated in statistical analysis of the real time RT-PCR, WJ participated in the HPLC experiments. BH conceived, designed and coordinated the study and revised the manuscript. All authors have read and approved of the final manuscript.”
“Background Melanoma and other skin cancers are still among the most serious public health problems. According to the World Health Organization, more than 210,000 skin cancer cases occur every year and about 66,000 patients die as a result.

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