In conclusion, four out of five common ozone-initiated terpene reaction products do not contribute substantially to sensory irritation symptoms and pulmonary effects at indoor or ambient concentrations. IPOH may contribute to sensory irritation and conditions that promote excessive formation of 4-OPA should be minimized. Thus, exposure data for IPOH and 4-OPA are warranted. The authors declare no conflict of interest. This work was supported by Real Dania this website under the project CISBO (Center for Indoor Climate and Diseases in Dwellings) and the project “OFFICAIR”
(On the reduction of health effects from combined exposure to indoor air pollutants in modern offices) funded by the European Union 7th Framework (Agreement 265267) under the Theme: ENV.2010.1.2.2-1. “
“The Organisers of the IUTOX 2010 Conference regret that in the original printing of the above-mentioned Abstract, the text was produced incorrectly. The correct version of the Abstract is reproduced below. The Organisers would like to apologise for any inconvenience
this may have caused to the authors of this Abstract and the readers of the journal. P208-025 A study on histopathological changes of gastric parietal cells observed in beagle dogs with decreased food consumption Osamu Sawamoto, Tatsuru Fukuda, Yasutaka Hayami, Yoshifumi Nakashima Preclinical Assessment Department, Otsuka Pharmaceutical Factory, Inc., Japan Background: In toxicity studies, vacuolation of gastric parietal cells has been occasionally experienced in the beagle dogs with marked decrease in food Ergoloid consumption. In this poster, we present the histopathological HDAC inhibitor and ultrastructural features of the parietal cells observed in the stomach of beagle dogs with decreased food consumption. Materials and methods: Three 8-month-old male beagle dogs were given adequate calories and nutrients by total parenteral nutrition via a venous catheter for 13 days without oral feeding. Two control beagle dogs were intravenously
given 0.9% saline under oral feeding conditions. Stomach samples were taken for histopathology and electron-microscopy. Results: In histopathology, the vacuolation of gastric parietal cells (gastric gland) was seen in 2 of the 3 dogs given total parenteral nutrition without oral feeding. Morphological analysis of the parietal cells by TEM showed tightly closed intracellular canaliculus, increase in the tubulovesicle structure, and/or numerous cytoplasmic vacuoles as compared with the control dogs. These vacuoles contained concentric multilayer membrane structure and/or fluffy substance. Conclusions: It is known that parietal cells of the stomach secretes gastric acid in response to oral feeding, and the cells morphologically change depending on the presence or absence of feeding. It is reported that vacuolation of parietal cells is induced when gastric acid secretion is inhibited by surgical treatment.