It was shown that for the most effective
hydrolysis of aspen wood pulp the optimal ratio of cellobiohydrolase and endo-1,4-beta-gluconase in enzyme preparations was 8: 2 (by protein). It was also established that the homologous xylanase secreted by the Penicillium canescens fungus is a required component for the enzyme complex for hydrolysis Fer-1 molecular weight of the hemicellulose matrix of aspen wood.”
“A simple, rapid, reliable and fully validated square wave adsorptive stripping voltammetric procedure has been developed for the determination of rifampicin drug in bulk form, capsules and human urine in acetate buffer pH 5.0 which shows electrochemical reduction at a new Dysprosium nanowires modified carbon paste electrode (DyNW/CPE).
In this paper, the modified carbon paste electrode (DyNW/CPE) exhibiting an electrocatalytic response toward the oxidation of RIF is described. The shift of the E(1/2) values of RIF to more negative potentials upon the increase of pH indicated the involvement of protons in the electrode reaction and that the proton-transfer reaction precedes the electrode process properly. Based on the interfacial adsorptive character of the drug onto the electrode, a validated direct square-wave adsorptive stripping voltammetric (SWAdSV) procedure has been described for the trace determination of the drug in pharmaceutical
and Bafilomycin A1 real samples. The catalytic action of the DyNW/CPE is attributed to the formation of the porous construction and the increase of efficient surface of the electrode, due to the adulteration of DyNW with carbon powders. The optimized operational conditions were investigated. The proposed procedure is much simpler, fast, sensitive, and achieved much lower limits. The limit of detection (LOD) 5.0 x 10(-10) M and limit of quantitation (LOQ) 8.0 x 10(-10) M was achieved respectively in pharmaceutical formulation and spiked human urine.”
“Decades of research have established
a PARP inhibitor model that includes the medial temporal lobe, and particularly the hippocampus, as a critical node for episodic memory. Neuroimaging and clinical studies have shown the involvement of additional cortical and subcortical regions. Among these areas, the thalamus, the retrosplenial cortex, and the prefrontal cortices have been consistently related to episodic memory performance. This article provides evidences that these areas are in different forms and degrees critical for human memory function rather than playing only an ancillary role. First we briefly summarize the functional architecture of the medial temporal lobe with respect to recognition memory and recall. We then focus on the clinical and neuroimaging evidence available on thalamo-prefrontal and thalamo-retrosplenial networks.