Nature 1978, 273:545–547.CrossRef 34. Moghimi SM, Hunter AC, Murray this website JC: Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev 2001, 53:283–318. 35. Sibrian-Vazquez M, Jensen TJ, Vicente MG: Synthesis,
characterization, and metabolic stability of porphyrin-peptide conjugates bearing bifunctional signaling sequences. J Med Chem 2008, 51:2915–2923.CrossRef 36. Romberg B, Hennink W, Storm G: Sheddable coatings for long-circulating nanoparticles. Pharm Res 2008, 25:55–71.CrossRef 37. Kohler N, Sun C, Wang J, Zhang M: Methotrexate-modified superparamagnetic find more nanoparticles and their intracellular uptake into human cancer cells. Langmuir 2005, 21:8858–8864.CrossRef 38. Samori C, Ali-Boucetta H, Sainz R, Guo C, Toma FM, Fabbro C, da Ros T, Prato M, Kostarelos K, Bianco A: Enhanced anticancer activity of multi-walled carbon nanotube-methotrexate conjugates using cleavable linkers. Chem Commun 2010, 46:1494–1496.CrossRef
39. Rai P, Padala C, Poon V, Saraph A, Basha S, Kate S, Tao K, Mogridge J, Kane RS: Statistical pattern matching facilitates the design BVD-523 of polyvalent inhibitors of anthrax and cholera toxins. Nat Biotechnol 2006, 24:582–586.CrossRef 40. Ashley CE, Carnes EC, Phillips GK, Padilla D, Durfee PN, Brown PA, Hanna TN, Liu J, Phillips B, Carter MB, Carroll NJ, Jiang X, Dunphy DR, Willman CL, Petsev DN, Evans DG, Parikh AN, Chackerian B, Wharton W, Peabody DS, Brinker CJ: The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. Nat Mater Phosphoprotein phosphatase 2011, 10:389–397.CrossRef 41. Jiang W, KimBetty YS, Rutka JT, ChanWarren CW: Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol 2008, 3:145–150.CrossRef 42. Mammen M, Choi S-K, Whitesides GM: Polyvalent interactions in biological systems: implications for design and use of multivalent
ligands and inhibitors. Angew Chem Int Ed 1998, 37:2754–2794.CrossRef 43. Pastan I, Hassan R, Fitzgerald DJ, Kreitman RJ: Immunotoxin therapy of cancer. Nat Rev Cancer 2006, 6:559–565.CrossRef 44. Licata NA, Tkachenko AV: Kinetic limitations of cooperativity-based drug delivery systems. Phys Rev Lett 2008, 100:158102–158105.CrossRef 45. Martinez-Veracoechea FJ, Frenkel D: Designing super selectivity in multivalent nano-particle binding. Proc Natl Acad Sci U S A 2011, 108:10963–10968.CrossRef 46. Wang S, Dormidontova EE: Selectivity of ligand-receptor interactions between nanoparticle and cell surfaces. Phys Rev Lett 2012, 109:238102.CrossRef 47. Jin E, Zhang B, Sun X, Zhou Z, Ma X, Sun Q, Tang J, Shen Y, Van Kirk E, Murdoch WJ, Radosz M: Acid-active cell-penetrating peptides for in vivo tumor-targeted drug delivery. J Am Chem Soc 2013, 135:933–940.CrossRef 48. Mohapatra S, Rout SR, Maiti S, Maiti TK, Panda AB: Monodisperse mesoporous cobalt ferrite nanoparticles: synthesis and application in targeted delivery of antitumor drugs. J Mater Chem 2011, 21:9185–9193.