Zepinelike in the action. However, although binding and behavioral outcomes suggest that teach not the GABA / benzodiazepine the angstl Send effect as the extract, this conclusion must be viewed with caution. The hypothesis deserves further investigation. Altogether, these results suggest that the extract Achillea act via a non-BDZ / Aminobutters Acid mechanism. This finding is interesting because it Yarrow of benzodiazepines, a class of drugs, the most prescribed anxiolytic, and other plants which have a different angstl Send effect. For example, flumazenil, at a dose that does not affect indices of FAK inhibitor in clinical trials behavior itself, blocks the angstl Send effect as of Cymbopogon citratus and Passiflora actinina. Apigenin, a big e exercise dose that corresponds to the content of 300 mg / kg extract of Achillea millefolium not any anxiolytic effects in the erh Buried Hten marble maze test. These results confirm to some non-VER Software released data on a angstl Send effect than 3.0 mg / kg increased testing at M F1 mice apigenin C Hten maze. However, Zanoli et al. and Avallone et al. non-compliance has no effect if the light / dark and increased Hten more maze in Sprague-Dawley rats. These contradictory results k Nnten on the differences between animal models and species or varieties. In addition, increased In hte mean dose of 1.0 mg / kg of apigenin, the number of buried marbles and the h HIGHEST dose of 3.0 mg / kg of apigenin decreased the proportion of entries into open arms and reflects the anxiety as the effect. These results are consistent with the apigenin-induced decrease in the latency of the Kr Vapors picrotoxin and apigenin-induced decrease in GABA-activated voltages induced.
Not reproduce in the same experimental conditions, the apigenin angstl Send effect as of Achillea millefolium extract, indicating that apigenin does not contribute to the angstl Send effect as Achillea millefolium extract in this study. Apigenin exercise) is not, no angstl Send effect as in the increased Buried Hten marble maze test. These results confirm to some non-VER Software released data on a angstl Send effect than 3.0 mg / kg increased testing at M F1 mice apigenin C Hten maze. However, Zanoli et al. and Avallone et al. non-compliance has no effect if the light / dark and increased Hten more maze in Sprague-Dawley rats. These contradictory results k Nnten on the differences between animal models and species or varieties. In addition, increased buy Streptozotocin In hte mean dose of 1.0 mg / kg of apigenin, the number of buried marbles and the h HIGHEST dose of 3.0 mg / kg of apigenin decreased the proportion of entries into open arms and reflects the anxiety as the effect. These results are consistent with the apigenin-induced decrease in the latency of the Kr Vapors picrotoxin and apigenin-induced decrease in GABA-activated voltages induced. Not reproduce in the same experimental conditions, the apigenin angstl Send effect as of Achillea millefolium extract, indicating that apigenin does not contribute to the angstl Send effect as Achillea millefolium extract in this study. Bemegride, barbiturate antagonist, but not flumazenil, a benzodiazepine antagonist azepine.