His report of the ACTH effects on infantile spasms was one of the early studies, only two years after Sorel’s original observation. His low-dose ACTH formula has been widely taken in Japan with fewer side effects than in other countries. The concept of benign AZD2014 price infantile convulsions published in 1963 was the first proposal, almost 30 years before Vigevano’s report in 1992. He was an extremely hard worker and a perfectionist.

For example, he collected about 1000 epilepsy-related books published since 1945. A collection of this size, according to his own estimation, was unavailable in Medline or any other existing electronic databases as of 2004. He was a fanatic collector of medical literature. The basement of his house is full of medical materials, and he stated that this collection was probably one of the richest libraries of child neurology and epileptology in the world. In addition to these medical activities, he always paid attention to international affairs. In 1979 he was elected an Executive Board member of the International Child Neurology Association (ICNA) along with me, and we attended Board meetings at least once a year in various parts of the world. Once, during such a meeting in

a small town in the Netherlands, we both began running for exercise on the seashore in the early morning. These occasions stimulated pleasant talks among the ICNA colleagues attending the meeting. however He was FG-4592 solubility dmso President of ICNA (1982–1986), and I followed him later as President (1994–1998). During these days, I came

to know him more personally than before, although I had been his student since my medical school and pediatric training days. In 1990, as Congress President, he organized the Joint Convention of the 5th International Child Neurology Congress and the 3rd Asian and Oceanian Congress of Child Neurology in Tokyo. I served him as Secretary, and almost 1000 participants attended this meeting, which remains known for its great success in the history of ICNA. One day in the late 1970s he talked to me about publishing a new child neurology journal in English, in addition to the Japanese version, No to Hattatsu, that had been regularly published since 1969. After this personal discussion, he immediately started negotiating with a publishing company and recruiting new editorial board members. Accordingly, he was the founder and first editor-in-chief of this journal, entitled Brain & Development. He held this position for 16 years (1979–1996). He devoted unbelievable time to this editorial job, carefully reading every paper for publication in detail. For this reason he often had to stay in his office until late at night, and very often he drove me on his way home, after he left work. He once commented that one-third of his working time was spent editing Brain & Development.