Setting: Tertiary referral center.
Patients: Thirty-two subjects with severe to profound hearing loss that developed before the age of 4.
Interventions: Subjects were implanted at a mean age of 24.8 years (range, 16-44) with Nucleus CI24 (n = 18, 56%), Clarion HiRes 90K(n = 11, 34%), and Medel PULSA(n = 3, 10%) device. Details of etiology, duration of deafness,
hearing aid history, hearing thresholds before operation, communication mode, and educational environment were investigated. Speech perception tests were performed preoperatively and 12 months after the operation.
Main ABT-737 datasheet Outcome Measures: Postoperative speech perception test scores between different options within patient group.
Results: The results showed significant improvement in
open set speech perception (sentence) scores after the implantation (mean scores from 7.0 to 46.7, p G 0.05). Preoperative hearing of better ear and preoperative speech perception scores correlated with postoperative performances (r = -0.70 and r = 0.46, respectively, p G 0.05). Education and communication mode were also closely related to postoperative performances. In the group with poorer performances, preoperative hearing thresholds were significantly worse than those with better performances, and a larger portion of those patients attended special schools and used sign language.
Conclusion: We found that residual auditory capacity in the better ear is an important factor in predicting outcomes after cochlear implantation in patients with NSC23766 concentration prelingual hearing loss.”
“Objective. We sought to determine whether placement of laminaria tents improve time to delivery compared with misoprostol alone in second trimester labor induction.
Methods. We retrospectively reviewed all patients undergoing second trimester labor induction. Patients with ruptured membranes, abruption, cervical dilation and chorioamnionitis at presentation were excluded. Complications were defined as chorioamnionitis,
retained placenta or other surgical procedures. Patients who received laminaria and vaginal misoprostol, 200 mu g every 12 h, were compared to those who received BIBF 1120 cell line misoprostol without laminaria.
Results. Forty-three patients met inclusion criteria, 19 underwent induction with misoprostol alone and 24 with laminaria and misoprostol. The median times to fetal and placenta deliveries were 16.4 and 0.0 h in the misoprostol group, and 20.6 and 0.2 h in the laminaria group. There was no difference in complications. Post-hoc power analysis revealed > 80% power to detect a difference in time to delivery of > 12 h, and > 90% power to detect a difference in time to placental delivery of >= 30 min.
Conclusions. Placement of laminaria does not improve fetal or placental delivery times in patients undergoing second trimester pregnancy termination by labor induction.